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Apoptosis and Programmed Cell Death Assessment

Apoptosis and programmed cell death assessment​ are critical components of understanding cellular lifecycle and disease progression, especially in cancer research. These processes involve a highly regulated sequence of events leading to cellular self-destruction, which is essential for maintaining tissue homeostasis and eliminating damaged cells. Researchers employ various techniques to assess apoptosis and programmed cell death, such as flow cytometry, caspase activity assays, and TUNEL staining, to quantify and analyze these events. Accurate assessment is crucial for developing therapies targeting dysregulated cell death pathways, offering potential advancements in treating diseases where apoptosis is impaired or excessively activated, such as cancer and neurodegenerative disorders.